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\u8d8a\u6765\u8d8a\u590d\u6742<\/strong><\/p>\n\n\n\n

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\u4e0d\u8fc7\uff0cLancaster\u548c\u5176\u4ed6\u5927\u591a\u6570\u7814\u7a76\u4eba\u5458\u8ba4\u4e3a\uff0c\u590d\u6d3b\u732a\u8111\u8fd9\u7c7b\u5bf9\u8c61\u6bd4\u7c7b\u5668\u5b98\u66f4\u5bb9\u6613\u4ea7\u751f\u610f\u8bc6\u3002\u7531\u795e\u7ecf\u79d1\u5b66\u5bb6Nenad Sestan\u9886\u5bfc\u7684\u732a\u8111\u7814\u7a76\u5c0f\u7ec4\uff0c\u76ee\u7684\u662f\u627e\u5230\u590d\u6d3b\u5668\u5b98\u7684\u65b0\u65b9\u6cd5\uff0c\u800c\u4e0d\u662f\u521b\u9020\u610f\u8bc6\u3002\u7814\u7a76\u4eba\u5458\u80fd\u591f\u8ba9\u5355\u4e2a\u795e\u7ecf\u5143\u6216\u795e\u7ecf\u5143\u7ec4\u653e\u7535\uff0c\u5e76\u5c0f\u5fc3\u7ffc\u7ffc\u5730\u8bd5\u56fe\u907f\u514d\u4ea7\u751f\u5927\u8303\u56f4\u7684\u8111\u7535\u6ce2\u3002\u4e0d\u8fc7\uff0c\u5f53Sestan\u7684\u56e2\u961f\u5728\u5176\u4e2d\u4e00\u4e2a\u5927\u8111\u4e2d\u770b\u5230\u8c8c\u4f3c\u534f\u8c03\u7684\u8111\u7535\u6d3b\u52a8\u65f6\uff0c\u4ed6\u4eec\u7acb\u5373\u505c\u6b62\u4e86\u8fd9\u4e2a\u9879\u76ee\u3002\u5373\u4f7f\u5728\u795e\u7ecf\u5b66\u4e13\u5bb6\u786e\u8ba4\u8be5\u6a21\u5f0f\u4e0e\u610f\u8bc6\u4e0d\u4e00\u81f4\u540e\uff0c\u4e3a\u4e86\u4ee5\u9632\u4e07\u4e00\uff0c\u8be5\u5c0f\u7ec4\u8fd8\u662f\u5bf9\u5927\u8111\u8fdb\u884c\u4e86\u9ebb\u9189\u3002<\/p>\n\n\n\n

Sestan\u8fd8\u8054\u7cfb\u4e86\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\uff08NIH\uff09\uff0c\u5bfb\u6c42\u5173\u4e8e\u540e\u7eed\u5de5\u4f5c\u8be5\u5982\u4f55\u5c55\u5f00\u7684\u6307\u5bfc\u610f\u89c1\u3002\u7814\u7a76\u9662\u7684\u795e\u7ecf\u4f26\u7406\u5b66\u5c0f\u7ec4\uff0c\u5305\u62ecLunshof\u548c\u4fc4\u4ea5\u4fc4\u5dde\u514b\u5229\u592b\u5170\u51ef\u65af\u897f\u50a8\u5927\u5b66\u7684\u751f\u7269\u4f26\u7406\u5b66\u5bb6Insoo Hyun\uff0c\u8bc4\u4f30\u4e86\u8fd9\u9879\u5de5\u4f5c\uff0c\u5e76\u4e00\u81f4\u8ba4\u4e3aSestan\u5e94\u8be5\u7ee7\u7eed\u9ebb\u9189\u7814\u7a76\u7528\u7684\u5927\u8111\u3002\u4f46\u8be5\u8bc4\u4f30\u5c0f\u7ec4\u8fd8\u6ca1\u6709\u5236\u5b9a\u66f4\u901a\u7528\u7684\u89c4\u5b9a\uff0c\u4e5f\u6ca1\u6709\u4f8b\u884c\u8981\u6c42\u5bf9\u7c7b\u5668\u5b98\u8bfe\u9898\u8fdb\u884c\u751f\u7269\u4f26\u7406\u5b66\u8bc4\u4f30\uff0c\u56e0\u4e3a\u5176\u6210\u5458\u8ba4\u4e3a\u610f\u8bc6\u662f\u4e0d\u592a\u53ef\u80fd\u4ea7\u751f\u7684\u3002NIH\u4e5f\u6ca1\u6709\u5c31\u610f\u8bc6\u7684\u5b9a\u4e49\u8fbe\u6210\u4e00\u81f4\u3002\u201c\u8fd9\u771f\u7684\u5f88\u7075\u6d3b\uff0c\u6bcf\u4e2a\u4eba\u90fd\u6709\u81ea\u5df1\u7684\u5b9a\u4e49\uff0c\u201dHyun\u8bf4\uff0c\u201c\u5982\u679c\u4e0d\u80fd\u786e\u5b9a\u6211\u4eec\u8bf4\u7684\u662f\u540c\u4e00\u4ef6\u4e8b\uff0c\u6c9f\u901a\u5c31\u6210\u4e86\u5927\u95ee\u9898\u3002\u201d\u00a0<\/p>\n\n\n\n

\u5b9a\u4e49\u6a21\u7cca<\/strong><\/p>\n\n\n\n

\u6709\u4e9b\u4eba\u751a\u81f3\u8ba4\u4e3a\uff0c\u5c1d\u8bd5\u5728\u4efb\u4f55\u4e00\u79cd\u5b9e\u9a8c\u5ba4\u7ef4\u62a4\u7684\u5927\u8111\u4e2d\u8bc6\u522b\u610f\u8bc6\u90fd\u662f\u5f92\u52b3\u7684\u3002\u6bd4\u5229\u65f6\u5217\u65e5\u5927\u5b66\u7684\u795e\u7ecf\u5b66\u5bb6Steven Laureys\u8bf4\uff1a\u201c\u9274\u4e8e\u6211\u4eec\u4e0d\u4e86\u89e3\u610f\u8bc6\uff0c\u6211\u4eec\u6839\u672c\u4e0d\u53ef\u80fd\u8bf4\u51fa\u8fd9\u4e9b\u8111\u7ec6\u80de\u675f\u80fd\u601d\u8003\u6216\u611f\u77e5\u4ec0\u4e48\u3002\u201d\u4ed6\u7387\u5148\u5bf9\u690d\u7269\u4eba\u8fdb\u884c\u4e86\u4e00\u4e9b\u57fa\u4e8e\u6210\u50cf\u7684\u610f\u8bc6\u6d4b\u91cf\u3002\u201c\u6211\u4eec\u4e0d\u5e94\u8be5\u592a\u81ea\u5927\u3002\u201d\u4ed6\u8bf4\uff0c\u5e94\u8be5\u975e\u5e38\u8c28\u614e\u5730\u5f00\u5c55\u8fdb\u4e00\u6b65\u7684\u7814\u7a76\u3002 <\/p>\n\n\n\n

Laureys\u7b49\u4eba\u6307\u51fa\uff0c\u7c7b\u5668\u5b98\u7684\u7ecf\u5386\u5f88\u53ef\u80fd\u4e0e\u65e9\u4ea7\u513f\u3001\u6210\u5e74\u4eba\u7c7b\u6216\u732a\u7684\u7ecf\u5386\u6709\u5f88\u5927\u4e0d\u540c\uff0c\u4e0d\u80fd\u76f4\u63a5\u6bd4\u8f83\u3002\u6b64\u5916\uff0c\u7c7b\u5668\u5b98\u4e2d\u7684\u7ed3\u6784\u53ef\u80fd\u8fc7\u5c0f\uff0c\u65e0\u6cd5\u51c6\u786e\u6d4b\u91cf\u5176\u6d3b\u52a8\uff0c\u800c\u7c7b\u5668\u5b98\u7684\u8111\u7535\u6a21\u5f0f\u4e0e\u65e9\u4ea7\u513f\u5927\u8111\u7684\u76f8\u4f3c\u6027\u53ef\u80fd\u53ea\u662f\u5de7\u5408\u3002\u5176\u4ed6\u4ece\u4e8b\u5927\u8111\u7c7b\u5668\u5b98\u7814\u7a76\u7684\u79d1\u5b66\u5bb6\u4e5f\u540c\u610fLaureys\u7684\u89c2\u70b9\uff0c\u5373\u4e00\u4e2a\u7cfb\u7edf\u662f\u5426\u6709\u610f\u8bc6\u7684\u95ee\u9898\u53ef\u80fd\u662f\u65e0\u6cd5\u56de\u7b54\u7684\u3002\u8bb8\u591a\u4eba\u5b8c\u5168\u56de\u907f\u8fd9\u4e2a\u89c2\u70b9\u3002\u201c\u6211\u4e0d\u77e5\u9053\u4e3a\u4ec0\u4e48\u6211\u4eec\u8981\u95ee\u8fd9\u4e2a\u95ee\u9898\uff0c\u56e0\u4e3a\u8fd9\u4e2a\u7cfb\u7edf\u4e0d\u662f\u4eba\u7c7b\u7684\u5927\u8111\uff0c\u201d\u65af\u5766\u798f\u5927\u5b66\u7684\u795e\u7ecf\u79d1\u5b66\u5bb6Sergiu Pas\u00e7a\u8bf4\uff0c\u201c\u5b83\u4eec\u662f\u7531\u795e\u7ecf\u5143\u7ec4\u6210\u7684\uff0c\u795e\u7ecf\u5143\u6709\u7535\u6d3b\u52a8\uff0c\u4f46\u6211\u4eec\u5fc5\u987b\u4ed4\u7ec6\u601d\u8003\u5982\u4f55\u6bd4\u8f83\u5b83\u4eec\u3002\u201d<\/p>\n\n\n\n

Muotri\u5e0c\u671b\u4ed6\u7684\u7c7b\u5668\u5b98\u7cfb\u7edf\u81f3\u5c11\u5728\u67d0\u4e9b\u65b9\u9762\u53ef\u4ee5\u4e0e\u4eba\u7c7b\u5927\u8111\u76f8\u5ab2\u7f8e\uff0c\u8fd9\u6837\u4ed6\u5c31\u53ef\u4ee5\u7814\u7a76\u4eba\u7c7b\u7684\u75be\u75c5\u5e76\u627e\u5230\u6cbb\u7597\u65b9\u6cd5\u3002\u4ed6\u6709\u4e2a\u4eba\u52a8\u673a\uff1a\u4ed614\u5c81\u7684\u513f\u5b50\u60a3\u6709\u766b\u75eb\u548c\u81ea\u95ed\u75c7\u3002\u201c\u4ed6\u7684\u751f\u6d3b\u4e2d\u5145\u6ee1\u56f0\u96be\u3002\u201dMuotri\u8bf4\u3002\u5927\u8111\u7c7b\u5668\u5b98\u662f\u4e00\u4e2a\u5f88\u6709\u524d\u666f\u7684\u7814\u7a76\u901a\u9053\uff0c\u56e0\u4e3a\u5b83\u4eec\u518d\u73b0\u4e86\u5927\u8111\u8fde\u63a5\u7684\u6700\u65e9\u9636\u6bb5\uff0c\u8fd9\u5728\u4eba\u7c7b\u80da\u80ce\u53d1\u80b2\u65f6\u662f\u4e0d\u53ef\u80fd\u7814\u7a76\u7684\u3002\u4f46\u4ed6\u8bf4\uff0c\u5728\u6ca1\u6709\u4e00\u4e2a\u529f\u80fd\u5b8c\u5907\u7684\u5927\u8111\u7684\u60c5\u51b5\u4e0b\u7814\u7a76\u4eba\u7c7b\u5927\u8111\u75be\u75c5\uff0c\u5c31\u50cf\u7814\u7a76\u4e00\u4e2a\u4e0d\u4ea7\u751f\u80f0\u5c9b\u7d20\u7684\u80f0\u817a\u4e00\u6837\u3002\u201c\u4e3a\u4e86\u8fbe\u5230\u8fd9\u4e2a\u76ee\u7684\uff0c\u6211\u9700\u8981\u4e00\u4e2a\u771f\u6b63\u7c7b\u4f3c\u4e8e\u4eba\u8111\u7684\u5927\u8111\u7c7b\u5668\u5b98\u6a21\u578b\u3002\u6211\u53ef\u80fd\u9700\u8981\u4e00\u4e2a\u4f1a\u53d8\u5f97\u6709\u610f\u8bc6\u7684\u7c7b\u5668\u5b98\u3002\u201d<\/p>\n\n\n\n

Muotri\u8bf4\uff0c\u4ed6\u4e0d\u77e5\u9053\u4f7f\u7528\u54ea\u79cd\u5b9a\u4e49\u6765\u5224\u5b9a\u4e00\u4e2a\u7c7b\u5668\u5b98\u662f\u5426\u8fbe\u5230\u610f\u8bc6\u72b6\u6001\u3002\u4ed6\u8bf4\uff0c\u5728\u67d0\u4e00\u523b\uff0c\u7c7b\u5668\u5b98\u751a\u81f3\u53ef\u80fd\u5e2e\u52a9\u7814\u7a76\u4eba\u5458\u56de\u7b54\u5173\u4e8e\u5927\u8111\u5982\u4f55\u4ea7\u751f\u610f\u8bc6\u72b6\u6001\u7684\u95ee\u9898\u3002\u4f8b\u5982\uff0c\u52a0\u5dde\u5927\u5b66\u5723\u8fed\u6208\u5206\u6821\u7684\u6570\u5b66\u5bb6Gabriel Silva\u6b63\u5728\u7814\u7a76Muotri\u7684\u7c7b\u5668\u5b98\u7684\u795e\u7ecf\u6d3b\u52a8\uff0c\u4ee5\u5f00\u53d1\u4e00\u79cd\u63cf\u8ff0\u5927\u8111\u5982\u4f55\u4ea7\u751f\u610f\u8bc6\u7684\u7b97\u6cd5[6]\u3002\u4ed6\u7684\u9879\u76ee\u7531\u5fae\u8f6f\u63d0\u4f9b\u90e8\u5206\u8d44\u52a9\uff0c\u76ee\u6807\u662f\u521b\u9020\u4e00\u4e2a\u50cf\u4eba\u7c7b\u610f\u8bc6\u4e00\u6837\u5de5\u4f5c\u7684\u4eba\u5de5\u7cfb\u7edf\u3002<\/p>\n\n\n\n

\u76ee\u524d\uff0c\u65e0\u8bba\u662f\u7f8e\u56fd\u8fd8\u662f\u6b27\u6d32\uff0c\u90fd\u6ca1\u6709\u963b\u6b62\u7814\u7a76\u4eba\u5458\u521b\u9020\u610f\u8bc6\u7684\u89c4\u5b9a\u3002\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u8bc4\u4f30\u5c0f\u7ec4\u8ba1\u5212\u5728\u660e\u5e74\u521d\u53d1\u5e03\u4e00\u4efd\u62a5\u544a\uff0c\u6982\u8ff0\u6700\u65b0\u7684\u7814\u7a76\u60c5\u51b5\uff0c\u5e76\u5bf9\u662f\u5426\u9700\u8981\u51fa\u53f0\u89c4\u5b9a\u505a\u51fa\u5224\u65ad\u3002\u6210\u5458\u4eec\u8ba1\u5212\u8003\u8651\u7684\u95ee\u9898\u5305\u62ec\uff1a\u662f\u5426\u9700\u8981\u5f81\u5f97\u4e00\u4e2a\u4eba\u7684\u540c\u610f\u624d\u80fd\u5c06\u5176\u7ec6\u80de\u57f9\u517b\u6210\u5927\u8111\u7c7b\u5668\u5b98\uff1b\u5982\u4f55\u4eba\u9053\u5730\u7814\u7a76\u548c\u5904\u7f6e\u7c7b\u5668\u5b98\u7b49\u3002\u56fd\u9645\u5e72\u7ec6\u80de\u7814\u7a76\u5b66\u4f1a\u4e5f\u5728\u5236\u5b9a\u7c7b\u5668\u5b98\u6307\u5357\uff0c\u4f46\u6ca1\u6709\u6d89\u53ca\u610f\u8bc6\u95ee\u9898\uff0c\u56e0\u4e3a\u5b83\u8ba4\u4e3a\u76f8\u5173\u7814\u7a76\u8fd8\u4e0d\u6210\u719f\u3002 <\/p>\n\n\n\n

Hyun\u8bf4\uff0c\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\u795e\u7ecf\u4f26\u7406\u5b66\u5c0f\u7ec4\u8fd8\u6ca1\u6709\u770b\u5230\u4efb\u4f55\u8981\u521b\u9020\u590d\u6742\u3001\u6709\u610f\u8bc6\u7684\u7c7b\u5668\u5b98\u7684\u7814\u7a76\u8ba1\u5212\u2014\u2014\u5982\u679c\u51fa\u73b0\u8fd9\u7c7b\u7814\u7a76\uff0c\u5c31\u610f\u5473\u7740\u5fc5\u987b\u5236\u5b9a\u65b0\u7684\u6307\u5357\u3002Muotri\u8bf4\uff0c\u4ed6\u4e0d\u77e5\u9053\u8fd8\u6709\u8c01\u60f3\u523b\u610f\u521b\u9020\u6709\u610f\u8bc6\u7684\u7c7b\u5668\u5b98\uff0c\u867d\u7136\u6839\u636e\u67d0\u4e9b\u5b9a\u4e49\uff0c\u4e00\u4e2a\u8db3\u591f\u590d\u6742\u7684\u7c7b\u5668\u5b98\u53ef\u80fd\u4f1a\u5076\u7136\u8fbe\u5230\u610f\u8bc6\u72b6\u6001\u3002<\/p>\n\n\n\n

\u4e0d\u8fc7\uff0cMuotri\u7b49\u4eba\u8868\u793a\uff0c\u4ed6\u4eec\u8fd8\u662f\u6b22\u8fce\u4e00\u4e9b\u6307\u5bfc\u65b9\u9488\u2014\u2014\u5305\u62ec\u8981\u6c42\u79d1\u5b66\u5bb6\u8bf4\u660e\u4ed6\u4eec\u4f7f\u7528\u7684\u4eba\u8111\u7c7b\u5668\u5b98\u7684\u6570\u91cf\uff1b\u53ea\u7528\u4e8e\u4e0d\u80fd\u4ee5\u4efb\u4f55\u5176\u4ed6\u65b9\u5f0f\u8fdb\u884c\u7684\u7814\u7a76\uff1b\u9650\u5236\u53ef\u80fd\u5bf9\u5b83\u4eec\u9020\u6210\u7684\u75db\u82e6\u7a0b\u5ea6\uff1b\u4eba\u9053\u5730\u5904\u7f6e\u5b83\u4eec\u3002<\/p>\n\n\n\n

\u63d0\u524d\u5236\u5b9a\u8fd9\u6837\u7684\u6307\u5357\uff0c\u5c06\u6709\u52a9\u4e8e\u7814\u7a76\u4eba\u5458\u6743\u8861\u521b\u9020\u610f\u8bc6\u5b9e\u4f53\u7684\u6210\u672c\u548c\u6536\u76ca\u3002\u8bb8\u591a\u7814\u7a76\u4eba\u5458\u5f3a\u8c03\uff0c\u8fd9\u79cd\u5b9e\u9a8c\u6709\u53ef\u80fd\u5e26\u6765\u91cd\u8981\u7684\u6d1e\u5bdf\u3002\u201c\u6709\u4e00\u4e9b\u771f\u6b63\u6709\u610f\u8bc6\u7684\u4eba\u60a3\u4e86\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\uff0c\u4f46\u6ca1\u6709\u6cbb\u7597\u65b9\u6cd5\u3002\u201dLancaster\u8bf4\u3002\u201c\u5982\u679c\u6211\u4eec\u771f\u7684\u56e0\u4e3a\u54f2\u5b66\u601d\u60f3\u5b9e\u9a8c\u800c\u505c\u6b62\u4e86\u6240\u6709\u8fd9\u4e9b\u7814\u7a76\uff0c\u201d\u5979\u8865\u5145\u9053\uff0c\u201c\u90a3\u5c06\u4f1a\u5bf9\u90a3\u4e9b\u786e\u5b9e\u9700\u8981\u67d0\u79cd\u65b0\u578b\u6cbb\u7597\u65b9\u6cd5\u7684\u5b9e\u9645\u4eba\u7c7b\u975e\u5e38\u4e0d\u5229\u3002\u201d<\/p>\n\n\n\n

\u7136\u800c\uff0c\u6cbb\u7597\u65b9\u6cd5\u4ecd\u53ef\u5728\u4f7f\u7528\u5c0f\u9f20\u5e72\u7ec6\u80de\u5236\u6210\u7684\u5927\u8111\u7c7b\u5668\u5b98\u6216\u6b63\u5e38\u7684\u52a8\u7269\u6a21\u578b\u4e2d\u8fdb\u884c\u6d4b\u8bd5\u3002\u8fd9\u6837\u7684\u5b9e\u9a8c\u4e5f\u53ef\u4ee5\u4e3a\u56f4\u7ed5\u4eba\u4f53\u7c7b\u5668\u5b98\u7684\u4f26\u7406\u5e94\u7528\u7684\u8ba8\u8bba\u63d0\u4f9b\u4fe1\u606f\u3002\u4f8b\u5982\uff0cHyun\u5e0c\u671b\u770b\u5230\u7814\u7a76\u4eba\u5458\u5c06\u5c0f\u9f20\u5927\u8111\u7c7b\u5668\u5b98\u7684\u8111\u7535\u56fe\u6a21\u5f0f\u4e0e\u6d3b\u4f53\u5c0f\u9f20\u7684\u8111\u7535\u56fe\u6a21\u5f0f\u8fdb\u884c\u6bd4\u8f83\uff0c\u8fd9\u6216\u8bb8\u80fd\u63ed\u793a\u4eba\u4f53\u7c7b\u5668\u5b98\u80fd\u5728\u591a\u5927\u7a0b\u5ea6\u4e0a\u518d\u73b0\u4eba\u7c7b\u5927\u8111\u3002<\/p>\n\n\n\n

Muotri\u8ba4\u4e3a\u7814\u7a76\u4eba\u4f53\u7c7b\u5668\u5b98\u548c\u7814\u7a76\u5b9e\u9a8c\u5ba4\u5c0f\u9f20\u51e0\u4e4e\u6ca1\u6709\u533a\u522b\u3002\u201c\u6211\u4eec\u5728\u7814\u7a76\u4e2d\u4f7f\u7528\u7684\u662f\u6709\u610f\u8bc6\u7684\u52a8\u7269\u6a21\u578b\uff0c\u4f46\u8fd9\u6ca1\u6709\u4efb\u4f55\u95ee\u9898\u3002\u201d\u4ed6\u8bf4\uff0c\u201c\u6211\u4eec\u9700\u8981\u5411\u524d\u8fdb\uff0c\u5982\u679c\u6700\u540e\u7c7b\u5668\u5b98\u53d8\u5f97\u6709\u610f\u8bc6\uff0c\u8bf4\u5b9e\u8bdd\uff0c\u6211\u4e0d\u8ba4\u4e3a\u90a3\u662f\u4e00\u4e2a\u5927\u95ee\u9898\u3002\u201d<\/p>\n\n\n\n

\u53c2\u8003\u6587\u732e\uff1a<\/p>\n\n\n\n

1. Trujillo, C. A. et al. Cell Stem Cel<\/em>l <\/em>25<\/strong>, 558\u2013569 (2019).<\/p>\n\n\n\n

2. Vrselja, Z. et al. Nature <\/em>568<\/strong>, 336\u2013343 (2019).<\/p>\n\n\n\n

3. Monti, M. M. et al. N. Engl. J. Med. <\/em>362<\/strong>, 579\u2013589 (2010).<\/p>\n\n\n\n

4. Giandomenico, S. L. et al. Nature Neurosci. <\/em>22<\/strong>, 669\u2013679 (2019).<\/p>\n\n\n\n

5. Quadrato, G. et al. Nature <\/em>545<\/strong>, 48\u201353 (2017).<\/p>\n\n\n\n

6. Silva, G. A., Muotri, A. R. & White, C. Preprint at biorXiv https:\/\/doi.org\/10.1101\/2020.07.28.225631 (2020).<\/p>\n\n\n\n

\u539f\u6587\u4ee5Can lab-grown brains become conscious?\u4e3a\u6807\u9898\u53d1\u8868\u5728 2020\u5e7410\u670827\u65e5\u7684\u300a\u81ea\u7136\u300b\u8bc4\u8bba\u7248\u5757<\/em><\/p>\n\n\n\n

\u539f\u6587\u4f5c\u8005\uff1aSara Reardon<\/p>\n\n\n\n

\u7248\u6743\u58f0\u660e\uff1a<\/p>\n\n\n\n

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